Cocaine-associated ischemic colitis.

J D Linder; K E Mönkemüller; I Raijman; L Johnson; A J Lazenby; C M Wilcox

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PubMed · 11005354

Cocaine-associated ischemic colitis.

J D Linder·K E Mönkemüller·I Raijman·L Johnson·A J Lazenby·C M Wilcox

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Abstract

Cocaine use can result in various gastrointestinal complications, including gastric ulcerations, retroperitoneal fibrosis, visceral infarction, intestinal ischemia, and gastrointestinal tract perforation. We report cocaine-associated colonic ischemia in three patients and review the literature. Including ours, 28 cases have been reported, with a mean patient age of 32.6 years (range, 23 to 47 years); 53.5% were men and 46.5% were women. The interval between drug ingestion and onset of symptoms varied from 1 hour to 2 days. Cocaine is a potentially life-threatening cause of ischemic colitis and should be included in the differential diagnosis of any young adult or middle-aged patient with abdominal pain and bloody diarrhea, especially in the absence of estrogen use or systemic disorders that can cause thromboembolic events, such as atrial fibrillation.

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Abdominal Pain Adult Cocaine-Related Disorders Colitis, Ischemic Crack Cocaine Diagnosis, Differential Diarrhea Female Gastrointestinal Hemorrhage Humans Male Middle Aged Sigmoidoscopy Time Factors Tomography, X-Ray Computed Case Reports Journal Article Review

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J D Linder, K E Mönkemüller, I Raijman, L Johnson, A J Lazenby, C M Wilcox. 2000. Cocaine-associated ischemic colitis.. https://pubmed.ncbi.nlm.nih.gov/11005354/

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