A synthetic transmembrane polyether model active in lipid bilayers.

C G Espínola; R Pérez; J D Martín

doi:10.1021/ol0063555

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PubMed · 11009371

A synthetic transmembrane polyether model active in lipid bilayers.

C G Espínola·R Pérez·J D Martín

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Abstract

A model polyether-based ion channel-like compound was rationally designed and synthesized. Macromolecules 1c-f were incorporated into phospholipid vesicles and shown to facilitate the transmembrane sodium transport.

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Alkenes Ethers Lipid Bilayers Membranes, Artificial Models, Molecular Polymers Potassium Channels Protein Conformation Sodium Radioisotopes Journal Article Research Support, Non-U.S. Gov't

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C G Espínola, R Pérez, J D Martín. 2000-10-05. A synthetic transmembrane polyether model active in lipid bilayers.. https://doi.org/10.1021/ol0063555

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