PubMed Health⌕ Search

PubMed · 11044315

Modifications to the cavopulmonary anastomosis do not eliminate early sinus node dysfunction.

Abstract

OBJECTIVE: To determine whether operations that theoretically jeopardize the sinus node (hemi-Fontan and/or lateral tunnel Fontan procedures) are associated with a greater risk of sinus node dysfunction than those that theoretically spare the sinus node (bidirectional Glenn and/or extracardiac conduit). METHODS: Between January 1, 1996, and December 31, 1999, a prospective cohort study was conducted evaluating the incidence of sinus node dysfunction in patients undergoing a bidirectional Glenn or hemi-Fontan procedure and those in whom the Fontan repair was completed with either an extracardiac conduit or a lateral tunnel. Sinus node dysfunction was defined (1) as a heart rate more than 2 SD below age-adjusted norms or (2) as a predominant junctional rhythm and/or a sinus pause of more than 3 seconds as determined by the resting electrocardiogram and/or ambulatory monitoring at hospital discharge. RESULTS: Fifty-one patients had a bidirectional Glenn shunt (mean age 7.8 +/- 5.1 months) and 79 a hemi-Fontan procedure (mean age 6.9 +/- 2.8 months). The incidence of sinus node dysfunction on postoperative day 1 was significantly higher after the hemi-Fontan (36%) than after the bidirectional Glenn shunt (9.8%); however, by hospital discharge this difference was no longer apparent (hemi-Fontan [8%]; bidirectional Glenn [6%]; P = not significant). No difference in early sinus node dysfunction was discernible after the extracardiac conduit (4/30 [13%]) compared with the lateral tunnel Fontan procedure (6/46 [13%]) (P = not significant). No diagnostic or perioperative variables were predictive of sinus node dysfunction. CONCLUSIONS: Avoidance of surgery near the sinus node has no discernible effect on the development of early sinus node dysfunction. Thus, concerns about early sinus node dysfunction should not override patient anatomy or surgeon preference as determinants of which cavopulmonary anastomosis to perform.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

M I Cohen, N D Bridges, J W Gaynor, T M Hoffman, G Wernovsky, V L Vetter, T L Spray, L A Rhodes. 2000. Modifications to the cavopulmonary anastomosis do not eliminate early sinus node dysfunction.. https://doi.org/10.1067/mtc.2000.109708

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Revival of the side-to-side approach for distal coronary anastomosis.

Side-to-side anastomosis was employed by just ten proportional stitches while performing distal anastomosis during coronary artery surgery. This technique is simple and quick. Here this simple technique is described in detail and the postoperative status of grafted conduits is reported.

Anastomosis, Surgical↗

Review article: Indeterminate colitis--definition, diagnosis and management.

BACKGROUND: The term indeterminate colitis is imprecise and without a generally accepted definition. Nevertheless, it is a term that is commonly used by gastroenterologists, pathologists and surgeons. AIM: To offer an opinion supported by published data, about the appropriate use of the term indeterminate colitis by addressing a series of questions. METHODS: A PubMed database search was performed using the keywords, 'colitis' and 'inflammatory bowel disease' each combined individually with the following adjectives: 'indeterminate', 'unclassified', 'undefined', 'undiagnosed' and 'non-specific'. RESULTS: There is no generally accepted definition of indeterminate colitis. All current applications of the term rely on exclusionary criteria and there is no confirmatory diagnostic test. Nevertheless, the diagnosis of indeterminate colitis appears to be durable in a subgroup of patients, suggesting that this group represents a unique phenotype. CONCLUSIONS: Indeterminate colitis has expanded from a strictly defined, postcolectomy pathological diagnosis to become, in addition, a clinical diagnosis without generally accepted criteria. A diagnosis of indeterminate colitis should be qualified with descriptors for the diagnostic criteria applied.

Anastomosis, Surgical↗

Acellular dermal matrix grafts for prevention of microarterial thrombophlebitis.

OBJECTIVE: To examine the role of acellular dermal matrix grafts for prevention of microarterial anastomotic thrombophlebitis. DESIGN: Bilateral femoral artery microvascular anastomoses were created in the field of established wounds infected with Staphylococcus aureus in 12 rats. In each animal, 1 femoral microarterial anastomosis was wrapped with an acellular dermal matrix graft, and the contralateral femoral anastomosis was left unprotected. The incidence of femoral artery thrombosis was determined after 4 days by wound reexploration. SETTING: David Geffen School of Medicine, University of California, Los Angeles. MAIN OUTCOME MEASURE: The patency of femoral artery anastomoses was determined after 4 days by wound reexploration. RESULTS: The incidence of femoral artery thrombosis in vessels wrapped with acellular dermal matrix grafts was 17%. The incidence of femoral artery thrombosis in unprotected vessels was 100%. This difference was statistically significant (P<.05). CONCLUSION: Acellular dermal matrix grafts seem to have a protective effect in the prevention of acute thrombophlebitis when arterial microvascular anastomoses are performed in infected surgical fields.

Anastomosis, Surgical↗