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PubMed · 11073128

Bronchiolitis in infants.

A Cantani
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Abstract

Bronchiolitis is a common disease of the lower respiratory tract of infants, resulting from inflammatory obstruction of the small airways. It is a predominant viral illness, in which the RSV (respiratory syncytial virus) is the agent in more that 50% of cases. It is not known how many children with genetic predisposition to atopy develop asthma symptoms after bronchiolitis, however the relationship between the two affections is not understood. We show that a major proportion of babies with a positive family history develops asthma at a younger age.

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BronchiolitisHumansInfantInfant, NewbornRetrospective StudiesJournal Article

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A Cantani. Bronchiolitis in infants.. https://pubmed.ncbi.nlm.nih.gov/11073128/

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PubMed2006

Chest radiography in children aged 2-59 months diagnosed with non-severe pneumonia as defined by World Health Organization: descriptive multicentre study in Pakistan.

OBJECTIVES: To evaluate the chest radiographs of children diagnosed with non-severe pneumonia on the basis of the current World Health Organization guidelines (fast breathing alone) for radiological evidence of pneumonia. DESIGN: Descriptive analysis. SETTING: Outpatient departments of six hospitals in four cities in Pakistan. PARTICIPANTS: 2000 children with non-severe pneumonia were enrolled; 1932 children were selected for chest radiography. INTERVENTIONS: Two consultant radiologists used standardised WHO definitions to evaluate chest radiographs; no clinical information was made available to them. If they disagreed, the radiographs were read by a third radiologist; the final classification was based on agreement between two of the three radiologists. MAIN OUTCOME MEASURES: Presence or absence of pneumonia on radiographs. RESULTS: Chest radiographs were reported normal in 1519 children (82%). Radiological evidence of pneumonia was reported in only 263 (14%) children, most of whom had interstitial pneumonitis. Lobar consolidation was present in only 26 children. The duration of illness did not correlate significantly with the presence of radiological changes (relative risk 1.17, 95% confidence interval 0.91 to 1.49). CONCLUSION: Most children diagnosed with non-severe pneumonia on the basis of the current WHO definition had normal chest radiographs.

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