Progress in cardiovascular biology: PPAR for the course.

M A Lazar

doi:10.1038/83301

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Progress in cardiovascular biology: PPAR for the course.

M A Lazar

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Abstract

Studies on mice lacking the peroxisome proliferator-activated receptor (PPAR) suggest that PPAR ligands reduce lipid accumulation in foamy macrophages, and may target other receptors. These findings warrant an in-depth investigation into the gene regulatory mechanisms of PPAR ligands, which are currently being developed as drugs to treat atherosclerosis and diabetes.

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Animals CD36 Antigens Cardiovascular Physiological Phenomena Foam Cells Humans Ligands Lipoproteins, LDL Mice Mice, Knockout Receptors, Cytoplasmic and Nuclear Transcription Factors Journal Article Comment

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M A Lazar. 2001. Progress in cardiovascular biology: PPAR for the course.. https://doi.org/10.1038/83301

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