Prostate cancer: simplicity to complexity.

M E Peters; E A Ostrander

doi:10.1038/84739

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Prostate cancer: simplicity to complexity.

M E Peters·E A Ostrander

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Abstract

Prostate cancer is a complex disease to which a multitude of genetic and environmental factors contribute. Two new studies offer insights as to how the disease may arise and progress. The first describes mapping and cloning of a new candidate gene, ELAC2, whereas the second demonstrates how cooperation between Cdkn1b and Pten contribute to suppression of prostate tumors.

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Chromosome Mapping Cyclin-Dependent Kinase Inhibitor p21 Cyclins Cytogenetics Genes, Tumor Suppressor Genetic Predisposition to Disease Humans Male Neoplasm Proteins PTEN Phosphohydrolase Phosphoric Monoester Hydrolases Prostatic Neoplasms Tumor Suppressor Proteins Journal Article Comment

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M E Peters, E A Ostrander. 2001. Prostate cancer: simplicity to complexity.. https://doi.org/10.1038/84739

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