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Malignant hypophosphathaemic bone disease.

K Kozlowski·S Posen
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Abstract

A case of crippling osteoporosis with muscular weakness, hypophosphatemia, hyperparathyroidism, defective skeletal calcification and cartilage destruction is reported. The patient, a male was observed from the age of 2 1/2 until his death at the age of 33 years. This bone/cartilage disease failed to respond to phosphate supplementation, parathyroidectomy and calcitriol. We believe this may represent a hitherto undescribed entity.

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Bone Diseases, MetabolicChild, PreschoolDiagnosis, DifferentialHumansHypophosphatemiaMaleRadiographyCase ReportsJournal Article

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K Kozlowski, S Posen. 2001. Malignant hypophosphathaemic bone disease.. https://doi.org/10.1016/s0720-048x(00)00247-3

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