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PubMed · 11306335

Glycodelins.

M Seppälä·H Koistinen·R Koistinen
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Abstract

Glycodelin is a major glycoprotein that is synthesized in the endometrium in response to progesterone and relaxin exposure. Endometrium-derived glycodelin-A has contraceptive and immunosuppressive properties. Glycodelin is absent from the endometrium during the fertile periovulatory phase, but is synthesized in this tissue during the peri-implantation phase and is abundant during the last week of the luteal phase. Changes in local and/or circulating glycodelin concentrations have been observed in women with reproductive disorders. The chemical modification of glycodelins has resulted in compounds with antiviral activity.

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Amino Acid SequenceAnimalsCarbohydrate SequenceFallopian TubesFemaleGlycodelinGlycoproteinsGlycosylationHumansImmune ToleranceMolecular Sequence DataOvaryPregnancyPregnancy ProteinsProgesteroneRelaxinSemenUterusJournal ArticleResearch Support, Non-U.S. Gov'tReview

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M Seppälä, H Koistinen, R Koistinen. 2001. Glycodelins.. https://doi.org/10.1016/s1043-2760(00)00365-9

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