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PubMed · 11504181

5-Hydroxytryptamine (serotonin): biphasic dose responses.

E J Calabrese
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Abstract

This article briefly summarizes the occurrence of biphasic dose-response relationships associated with 5-hydroxytryptamine (5-HT) receptor systems, as well as 5-HT agonists and antagonists. Such biphasic responses have been reliably reported in multiple experimental settings that explored a broad range of responses, including aggressive behavior, cardiovascular functioning, muscle relaxation, and interactions with other receptor systems such as adrenergic interaction as well as with neurotransmitters such as NMDA.

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AggressionAnimalsCardiovascular Physiological PhenomenaDose-Response Relationship, DrugHumansKidneyMuscle RelaxationN-MethylaspartateReceptors, SerotoninSerotoninSerotonin AntagonistsSerotonin Receptor AgonistsSignal TransductionJournal ArticleReview

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BibTeXRIS

E J Calabrese. 2001. 5-Hydroxytryptamine (serotonin): biphasic dose responses.. https://doi.org/10.1080/20014091111820

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