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Abstract

The further development of Mechnikov's ideas is outlined, which was accomplished by the representatives of the Moscow School for General Pathology (founded by A. B. Focht) in terms of: 1) clarification of the mechanisms for adaptation of the organism under conditions of pathology and adoption of a general pathological approach in the explanation of pathological phenomena--by V. K. Lindemann; 2) in the field of endocrinology and gerontology--by V. G. Korenchevskii; 3) the problems of age-determined reactivity--by G. P. Saharov, author of the concept about the "organic immunity".