Enzymatically cleavable linker groups in polymer-supported synthesis.

Reinhard Reents; Duraiswamy A Jeyaraj; Herbert Waldmann

doi:10.1016/s1359-6446(01)02088-8

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Enzymatically cleavable linker groups in polymer-supported synthesis.

Reinhard Reents·Duraiswamy A Jeyaraj·Herbert Waldmann

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Abstract

Access to broadly applicable linker groups that are stable under a variety of reaction conditions and enable the release of target compounds from polymeric supports under the mildest conditions is a major goal in combinatorial chemistry. Here, we summarize the development of enzymatically cleavable linker groups used to prepare a variety of different target molecules on polymeric supports.

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Combinatorial Chemistry Techniques Enzymes Polymers Protein Conformation Journal Article Research Support, Non-U.S. Gov't Review

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Reinhard Reents, Duraiswamy A Jeyaraj, Herbert Waldmann. 2002-01-01. Enzymatically cleavable linker groups in polymer-supported synthesis.. https://doi.org/10.1016/s1359-6446(01)02088-8

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