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Neural plate patterning by secreted signals.

Oliver Wessely·E M De Robertis
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Abstract

The patterning of the CNS relies on the interaction of multiple signaling molecules such as Sonic Hedgehog, Wnts, and BMPs and their antagonists Chordin and Noggin. The identification of the secreted molecule Tiarin (Tsuda et al., 2002, this issue of Neuron), produced by the nonneural ectoderm at border of the anterior and lateral neural plate, now introduces a novel signaling pathway participating in CNS development.

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AnimalsBody PatterningCell DifferentiationCentral Nervous SystemEmbryonic InductionGene Expression Regulation, DevelopmentalGrowth SubstancesHumansSignal TransductionCommentJournal ArticleReview

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Oliver Wessely, E M De Robertis. 2002-02-14. Neural plate patterning by secreted signals.. https://doi.org/10.1016/s0896-6273(02)00596-2

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