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How should we grade CIN?

M K Heatley
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Abstract

How should we grade CIN? The grading of cervical intraepithelial neoplasia (CIN) is problematic. CIN represents a morphological continuum, but biopsies displaying this lesion are classified into two (e.g. Bethesda) or three grade categories, sometimes with poor reproducibility. There are also difficulties in reliably distinguishing low-grade CIN from its reactive simulants. Because of problems with inter- and intra-observer disagreement in the grading of CIN and the diagnosis of low-grade lesions, three expert contributions were commissioned to address the question 'how should we grade CIN?'.

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Diagnosis, DifferentialFemaleHumansSeverity of Illness IndexUterine Cervical NeoplasmsUterine Cervical DysplasiaJournal Article

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M K Heatley. 2002. How should we grade CIN?. https://doi.org/10.1046/j.1365-2559.2002.01365.x

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