High-speed combinatorial synthesis utilizing microwave irradiation.

C Oliver Kappe

doi:10.1016/s1367-5931(02)00306-x

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High-speed combinatorial synthesis utilizing microwave irradiation.

C Oliver Kappe

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Abstract

Recent advances in microwave-assisted combinatorial chemistry include high-speed solid-phase and polymer-supported organic synthesis, rapid parallel synthesis of compound libraries, and library generation by automated sequential microwave irradiation. In addition, new instrumentation for high-throughput microwave-assisted synthesis continues to be developed at a steady pace. The impressive speed combined with the unmatched control over reaction parameters justifies the growing interest in this application of microwave heating.

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Combinatorial Chemistry Techniques Microwaves Polymers Journal Article Review

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C Oliver Kappe. 2002. High-speed combinatorial synthesis utilizing microwave irradiation.. https://doi.org/10.1016/s1367-5931(02)00306-x

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