PubMed Health⌕ Search

PubMed · 12126180

Interview with Wallace D. Winters.

Abstract

Wallace Winters exemplifies the model of the basic scientist/clinical toxicologist. His extensive research interests have led to a better understanding of central nervous system excitation and depression, and have included pioneering studies on the neuropharmacology of gammahydroxy butyrate that date back to the 1960s. Dr. Winters was born in New York, NY on June 20, 1929. He received his undergraduate degree at George Washington University, his Ph.D. in Pharmacology/Toxicology at the University of Wisconsin, and his M.D. at the Medical College of Wisconsin. From 1959 to 1962 Dr. Winters pursued postdoctoral studies at the Brain Research Institute at University of California, Los Angeles where he remained on the faculty rising to full Professor. In 1971, Dr. Winters relocated to University of California at Davis where he served as a Professor of Pharmacology/Toxicology for the next 20 years. During this time, Dr. Winters founded the University of California Davis Poison Control Center in Sacramento in 1977 and served as its first medical director until 1983. From 1979 to 1984 he served on the American Academy of Clinical Toxicology Board of Trustees. After retiring from University of California, Davis, Dr. Winters worked as a Medical Officer for the U.S. Food and Drug Administration from 1991 to 1997, and continues to serve as a consultant and medical expert in clinical pharmacology and toxicology.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Wallace D Winters. 2002. Interview with Wallace D. Winters.. https://pubmed.ncbi.nlm.nih.gov/12126180/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

[Sexual medicine].

Explore the source record for details and available documents.

Clinical Medicine↗

Video and qualitative research: analysing medical practice and interaction.

CONTEXT: Video has long been recognised as providing an important resource within medical education, particularly, perhaps, for training in primary health care. As a resource for research, and more specifically within qualitative social science studies of medical practice, video has proved less pervasive, despite its obvious advantages. METHODS: In this paper, we sketch an approach to using video to inform the analysis of medical practice and the ways in which health care is accomplished through social interaction and collaboration. Drawing on our own research, we discuss two brief examples: the first involves the use of computing technology in primary health care and the second concerns informal instruction during surgery. The examples illustrate the multimodal character of medical work, how activities are accomplished through the interplay of talk, the visual and the use of material artefacts. They also illustrate the ways in which video provides access to the complex forms of social interaction and collaboration that underpin health care. DISCUSSION: We reflect upon the research opportunities afforded by video and the ways in which video-based studies of interaction can contribute to the practice and practicalities of medicine.

Clinical Medicine↗

Predictive data mining in clinical medicine: current issues and guidelines.

BACKGROUND: The widespread availability of new computational methods and tools for data analysis and predictive modeling requires medical informatics researchers and practitioners to systematically select the most appropriate strategy to cope with clinical prediction problems. In particular, the collection of methods known as 'data mining' offers methodological and technical solutions to deal with the analysis of medical data and construction of prediction models. A large variety of these methods requires general and simple guidelines that may help practitioners in the appropriate selection of data mining tools, construction and validation of predictive models, along with the dissemination of predictive models within clinical environments. PURPOSE: The goal of this review is to discuss the extent and role of the research area of predictive data mining and to propose a framework to cope with the problems of constructing, assessing and exploiting data mining models in clinical medicine. METHODS: We review the recent relevant work published in the area of predictive data mining in clinical medicine, highlighting critical issues and summarizing the approaches in a set of learned lessons. RESULTS: The paper provides a comprehensive review of the state of the art of predictive data mining in clinical medicine and gives guidelines to carry out data mining studies in this field. CONCLUSIONS: Predictive data mining is becoming an essential instrument for researchers and clinical practitioners in medicine. Understanding the main issues underlying these methods and the application of agreed and standardized procedures is mandatory for their deployment and the dissemination of results. Thanks to the integration of molecular and clinical data taking place within genomic medicine, the area has recently not only gained a fresh impulse but also a new set of complex problems it needs to address.

Clinical Medicine↗