PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 12201719

Ionic liquid acceleration of solid-phase suzuki-miyaura cross-coupling reactions.

Jefferson D Revell·A Ganesan
View original source ↗Export metadata ↓

Abstract

[reaction: see text] Room-temperature ionic liquids promote various transition metal-catalyzed reactions in the solution phase. Here, for the first time, we show that these effects are translatable to solid-phase reactions. The Suzuki-Miyaura cross-coupling of 4-iodophenol immobilized on polystyrene-Wang resin with various arylboronic acids was significantly accelerated by the ionic liquid 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim][BF(4)(-)]).

Explore related subjects

BoratesBoronic AcidsCatalysisCombinatorial Chemistry TechniquesEnvironmental PollutionEquipment ReuseImidazolesIndustrial WasteIodobenzenesIonsPalladiumResins, SyntheticSolventsJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

Jefferson D Revell, A Ganesan. 2002-09-05. Ionic liquid acceleration of solid-phase suzuki-miyaura cross-coupling reactions.. https://doi.org/10.1021/ol0263292

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2006

Self-assembling poly(dioxaborole)s as blue-emissive materials.

Conjugated, borole-linked polymers have been self-assembled based on boronate ester formation between a fluorene-2,7-diboronic acid and 1,2,4,5-tetrahydroxybenzene. Readily soluble polymers with molecular weights approaching 60 000 have been generated with materials exhibiting extended conjugation over approximately 3-5 borole linkages. Emission from these polymers reaches into the visible (blue) range, representing a novel class of blue-emitting materials.

Borates↗
PubMed2006

Application of ionic liquids in the microwave-assisted extraction of trans-resveratrol from Rhizma Polygoni Cuspidati.

In this paper, the application of 1-n-butyl -3-methylimidazolium-based ionic liquids aqueous solutions as solvents in the microwave-assisted extraction (MAE) technique was first developed for the extraction of trans-resveratrol from Rhizma Polygoni Cuspidati. 1-butyl-3-methylimidazolium bromide ([bmim]Br) solution was selected as solvent; the conditions of MAE including the size of sample, liquid/solid ratio, extraction temperature and time were optimized by means of an orthogonal design L(9)(3(4)). Under optimized conditions, the extraction yield value of trans-resveratrol was 92.8% in a one-step extraction. The recovery was in the range 93.7-103.2% with relative standard deviation lower than 3.0% by the proposed procedure. The method was applied to extract trans-resveratrol from several different region samples. On the basis of extraction solvent and time, the proposed extraction technique was a green, rapid and alternative technique to extract and analyze trans-resveratrol in Rhizma Polygoni Cuspidati samples.

Borates↗