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A new method for evaluating antitussives in cats using an electrode-cannula.

M W Talbott·G K Barch·L P Gabel
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Abstract

An emplaced laryngo-tracheal electrode-cannula was employed to induce and to measure cough in cats anesthetized with either sodium pentobarbital or Dial--urethane. Carbetapentane citrate, codeine sulfate and dextromethorphan hydrobromide were tested for antitussive action by this method. Relative antitussive potency obtained in order of decreasing effectiveness was dextromethorphan hydrobromide, codeine sulfate and carbetapentane citrate.

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AnimalsAntitussive AgentsCarboxylic AcidsCatheterizationCatsCodeineCoughDextromethorphanElectric StimulationElectrodesFemaleLarynxMaleTime FactorsTracheaJournal Article

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M W Talbott, G K Barch, L P Gabel. 1975. A new method for evaluating antitussives in cats using an electrode-cannula.. https://doi.org/10.1016/0014-2999(75)90225-3

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