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Tech.Sight. Phage display. Affinity selection from biological libraries.

James F Smothers·Steven Henikoff·Paul Carter
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Abstract

Phage display is a simple yet powerful technology that is used to rapidly characterize protein-protein interactions from amongst billions of candidates. This widely practiced technique is used to map antibody epitopes, create vaccines and to engineer peptides, antibodies and other proteins as both diagnostic tools and as human therapeutics. We overview the history of phage display and several recent applications.

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AnimalsAntibodiesAntibody AffinityBacteriophagesDatabases, ProteinEpitope MappingHumansNanotechnologyPeptide LibraryPeptidesProtein BindingProteinsRecombinant Fusion ProteinsSemiconductorsJournal Article

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James F Smothers, Steven Henikoff, Paul Carter. 2002-10-18. Tech.Sight. Phage display. Affinity selection from biological libraries.. https://doi.org/10.1126/science.298.5593.621

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