Tissue array technique for p53 expression in human ovarian neoplasms.

Yapin Wang; He Wang; Zhilan Peng; Kaixuan Yang

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PubMed · 12411037

Tissue array technique for p53 expression in human ovarian neoplasms.

Yapin Wang·He Wang·Zhilan Peng·Kaixuan Yang

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Abstract

OBJECTIVE: To investigate the expression of p53 in human ovarian neoplasms by tissue array technique. METHODS: The expression of p53 protein in various ovarian tissues was studied by tissue array and immunohistochemistry. RESULTS: The expression rate of p53 was 33% in ovarian cancers. There were no expressions in normal ovarian tissues, benign ovarian neoplasms and borderline ovarian neoplasms (P < 0.005). p53 expression was not associated with age of patients and grade of differentiation (P > 0.05) while p53 expression was associated with tissue types (P < 0.05). CONCLUSION: The expression rates of p53 in ovarian cancers were obviously increased.

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Female Humans Immunohistochemistry Ovarian Neoplasms Tumor Suppressor Protein p53 Journal Article

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Yapin Wang, He Wang, Zhilan Peng, Kaixuan Yang. 2002. Tissue array technique for p53 expression in human ovarian neoplasms.. https://pubmed.ncbi.nlm.nih.gov/12411037/

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