Connexin36 forms synapses essential for night vision.

Jonathan B Demb; Edward N Pugh

doi:10.1016/s0896-6273(02)01062-0

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Connexin36 forms synapses essential for night vision.

Jonathan B Demb·Edward N Pugh

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Abstract

Rod signals reach ganglion cells via at least five pathways. A new study in this issue of Neuron shows that all pathways from rods to ON-type ganglion cells require connexin36. This is the first physiological demonstration in mammals that a well-defined neural circuit requires a gap junction as an obligatory transmission step.

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Animals Connexins Dark Adaptation Eye Proteins Gap Junctions Humans Neural Pathways Retina Synapses Synaptic Transmission Vision, Ocular Gap Junction delta-2 Protein Comment Journal Article Review

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Jonathan B Demb, Edward N Pugh. 2002-11-14. Connexin36 forms synapses essential for night vision.. https://doi.org/10.1016/s0896-6273(02)01062-0

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