Upper airway abnormalities in Canavan disease.

Jethro Francois; Jose M Manaligod

doi:10.1016/s0165-5876(02)00258-6

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Upper airway abnormalities in Canavan disease.

Jethro Francois·Jose M Manaligod

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Abstract

OBJECTIVE: To describe upper airway anatomical abnormalities associated with Canavan disease. METHODS: Retrospective case report. RESULTS: Physical examination and laryngoscopy demonstrated oropharyngeal narrowing, macroglossia, and bronchial asymmetry in a child with Canavan disease. Tracheostomy decreased problems with chronic aspiration and obstructive sleep apnea. CONCLUSIONS: Oropharyngeal obstruction and bronchial asymmetry are previously undescribed upper airway abnormalities found in an individual with Canavan disease. Tracheostomy is an effective method of managing chronic aspiration and obstruction in these patients.

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Airway Obstruction Canavan Disease Child, Preschool Follow-Up Studies Humans Laryngoscopy Laryngostenosis Male Pneumonia, Aspiration Risk Assessment Severity of Illness Index Tracheostomy Case Reports Journal Article

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Jethro Francois, Jose M Manaligod. 2002-12-02. Upper airway abnormalities in Canavan disease.. https://doi.org/10.1016/s0165-5876(02)00258-6

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