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PubMed · 12474583

[Is dehydration an ethical problem?].

Krzysztof Marczewski·Andrzej Czernikiewicz·Jarosław Jerzy Sak·Anna Kwiecińska·Ahmad Mourad
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Abstract

In the paper, issues connected with chronic dehydration were discussed from the point of view of medical ethics. Rudimentary definitions concerning the issues were mentioned. An attempt was made at analysing critically the views on chronic voluntary dehydration as a possible form of causing death. Some pathophysiological and psychopathological aspects were discussed. "The pyramid" of physician doubts were presented.

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DehydrationEthical AnalysisEthics, ClinicalEthics, MedicalEuthanasia, Active, VoluntaryHumansPersonal AutonomyPhysician's RolePolandPublic OpinionSuicide, AssistedTreatment RefusalWithholding TreatmentEnglish AbstractJournal ArticleReview

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Krzysztof Marczewski, Andrzej Czernikiewicz, Jarosław Jerzy Sak, Anna Kwiecińska, Ahmad Mourad. 2002. [Is dehydration an ethical problem?].. https://pubmed.ncbi.nlm.nih.gov/12474583/

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Achievement of rapid osmotic dehydration at specific temperatures could maintain high Saccharomyces cerevisiae viability.

Various methods have been tried to prevent cell mortality during dehydration, but the reasons why microorganisms die when submitted to dehydration and rehydration are not well understood. The aim of this study was to further investigate the reasons for yeast mortality during dehydration. Osmotic dehydration and rehydration of Saccharomyces cerevisiae W303-1A were performed at different temperatures. Two different approaches were used: isothermic treatments (dehydration and rehydration at the same temperature), and cyclic treatments (dehydration at an experimental temperature and rehydration at 25 degrees C), with significant differences in viability found between the different treatments. Dehydration at lower and higher temperatures gave higher viability results. These experiments allowed us to propose a hypothesis that relates mortality to a high water flow through an unstable membrane during phase transition.

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