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PubMed · 1248122

Evaluation of a discrete-sample computer-directed clinical analyzer.

R L Forrester·W Collinge·P Hashimoto·J Worrall
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Abstract

The operational characteristics of the Gilford System 3500 were evaluated for six months as to accuracy, precision, carry-over, reliability, and ease of operation. Accuracy was evaluated by comparison to manual methods of established accuracy. The tests evaluated and their respective correlation coefficients are as follows: glucose (0.99), blood urea nitrogen (0.99), calcium (0.97), total bilirubin (0.99), aspartate aminotransferase (0.97), alkaline phosphatase (0.98), albumin (0.96), and total protein (0.96). Within-run precision (CV) for three commercial calibration sera of differing analyte concentrations (low, intermediate, and high) were respectively: 0.69, 1.02, 1.18; 5.4, 1.2, 1.09; 0.83, 0.77, 0.86; 5.9, 1.0, 0.86; 6.4, 5.2, 2.1; 3.7, 1.5, 1.3; 0.0, 1.4, 0.97; and 1.2, 1.3, 0.75. Day-to-day precision, similarly evaluated during 101-164 days, met accepted criteria for clinically acceptable precision. Carry-over for each of the eight tests was less than 1%. Instrument reliability has been excellent, and training time is short. In summary, we have found the Gilford System 3500 to be sufficiently precise and fast, easy to operate, highly accurate, and flexible.

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Alkaline PhosphataseAspartate AminotransferasesAutoanalysisBilirubinBlood Chemical AnalysisBlood GlucoseBlood ProteinsBlood Urea NitrogenCalciumComputersEvaluation Studies as TopicQuality ControlSerum AlbuminComparative StudyJournal Article

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R L Forrester, W Collinge, P Hashimoto, J Worrall. 1976. Evaluation of a discrete-sample computer-directed clinical analyzer.. https://pubmed.ncbi.nlm.nih.gov/1248122/

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