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PKG and the neural basis for behavioral phenotypes.

William R Schafer
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Abstract

Cyclic GMP-dependent protein kinase (PKG) has been implicated in the regulation of diverse aspects of vertebrate and insect behavior, yet the mechanisms underlying these effects are poorly understood. In this issue of Neuron, Fujiwara et al. and L'Etoile et al. address the neural basis for PKG function in C. elegans and demonstrate the power of behavioral genetic analysis in simple systems in the elucidation of neuronal signaling mechanisms in vivo.

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AnimalsBehavior, AnimalCaenorhabditis elegansCell CommunicationCyclic GMP-Dependent Protein KinasesGene Expression Regulation, DevelopmentalNervous SystemNeuronsPhenotypeSignal TransductionCommentJournal ArticleReview

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William R Schafer. 2002-12-19. PKG and the neural basis for behavioral phenotypes.. https://doi.org/10.1016/s0896-6273(02)01135-2

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