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A putative link between exocytosis and tumor development.

Andrew M Chan·Thomas Weber
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Abstract

Desmoplastic small round cell tumor (DSRCT) is characterized by a t(11;22)(p13;q12) translocation breakpoint. In this issue of Cancer Cell, now show that the resulting EWS-WT1 gene-fusion product leads to overexpression of BAIAP3, a protein implicated in regulated exocytosis.

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Angiogenesis InhibitorsAnimalsCarcinoma, Small CellExocytosisGene Expression RegulationHumansProteinsRNA-Binding Protein EWSSoft Tissue NeoplasmsTranslocation, GeneticCommentJournal Article

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Andrew M Chan, Thomas Weber. 2002. A putative link between exocytosis and tumor development.. https://doi.org/10.1016/s1535-6108(02)00210-6

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