PubMed · 12522722
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H A Adams, G Hempelmann, C Krier, J Schulte am Esch. 2003. [Note to our readers].. https://doi.org/10.1055/s-2003-36568
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Precision oncology relies on integrating tumour fraction, variant allele frequency, clonal haematopoiesis of indeterminate potential assessment, pathogenicity, and clinical context into next-generation sequencing interpretation, enabling biologically informed and clinically meaningful treatment decisions while reducing the risk of overinterpreting nontumour or nonactionable genomic alterations.