Synaptic cell adhesion goes functional.

Markus Missler

doi:10.1016/s0166-2236(03)00066-3

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PubMed · 12689765

Synaptic cell adhesion goes functional.

Markus Missler

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Abstract

A growing number of candidate genes has been implicated in linking the two sides of a synapse but definitive proof of a specific role for many of them is still scarce. Exploiting the vast amount of sequence data, a novel family of homophilic synaptic cell-adhesion molecules (SynCAMs) has now been identified in mice. SynCAMs are evolutionarily related to invertebrate immunoglobulin-like (Ig)-domain proteins and they promote the formation and differentiation of functional synapses in vitro.

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Animals Cell Adhesion Cell Adhesion Molecules Cell Adhesion Molecules, Neuronal Cell Line Hippocampus Immunoglobulins In Vitro Techniques Mice Neurons Rats Synapses Tumor Suppressor Proteins Journal Article Comment

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Markus Missler. 2003. Synaptic cell adhesion goes functional.. https://doi.org/10.1016/s0166-2236(03)00066-3

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