Stimulant-related state-dependent learning in hyperactive children.

J M Swanson; M Kinsbourne

doi:10.1126/science.1273596

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PubMed · 1273596

Stimulant-related state-dependent learning in hyperactive children.

J M Swanson·M Kinsbourne

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Abstract

Hyperactive and nonhyperactive children performed a learning task in two states, while being treated with stimulant medication (methylphenidate) and while taking a placebo, and were tested for retention of each class of learned material in both states. Symmetrical state-dependent learning was demonstrated in the hyperactive group but not in the nonhyperactive group. The state-dependent effect was contingent on the presence of drug-induced facilitation during initial learning. This is apparently the first report on record of state-dependent learning with a drug agent that facilitates rather than impairs performance of human subjects.

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Child Humans Hyperkinesis Learning Memory Methylphenidate Retention, Psychology Clinical Trial Controlled Clinical Trial Journal Article

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J M Swanson, M Kinsbourne. 1976-06-25. Stimulant-related state-dependent learning in hyperactive children.. https://doi.org/10.1126/science.1273596

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