Brain changes in glaucoma.

N Gupta; Y H Yücel

doi:10.1177/112067210301303s06

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PubMed · 12749675

Brain changes in glaucoma.

N Gupta·Y H Yücel

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Abstract

There is evidence that glaucomatous damage extends from retinal ganglion cells to vision centers in the brain. In the lateral geniculate nucleus (LGN), the major relay center between the eye and the visual cortex, neurons should undergo degenerative and/or neurochemical changes in magno-, parvo-, and koniocellular pathways conveying motion, red-green, and blue-yellow information, respectively. Furthermore, in both the LGN and visual cortex in glaucoma, changes in metabolic activity are observed. The study of brain changes in glaucoma may provide new insights into the pathobiology of glaucomatous damage and disease progression, and may stimulate new detection and therapeutic strategies to prevent blindness.

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Animals Apoptosis Geniculate Bodies Glaucoma Humans Nerve Degeneration Neurons Optic Nerve Diseases Retinal Ganglion Cells Visual Cortex Visual Pathways Journal Article Review

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N Gupta, Y H Yücel. 2003. Brain changes in glaucoma.. https://doi.org/10.1177/112067210301303s06

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