Skip to content

Home/Archive/PubMed

PubMed · 12782796

Making virtual screening a reality.

View original source ↗Export metadata ↓

Abstract

The source did not provide an abstract. Follow the original record for more information.

Explore related subjects

Drug Design Drug Evaluation, Preclinical Humans In Vitro Techniques Ligands Molecular Structure Receptors, Thyroid Hormone User-Computer Interface Comment Journal Article

Keep this discovery

Explore connections, maps & timelines

John T Koh. 2003-06-02. Making virtual screening a reality.. https://doi.org/10.1073/pnas.1332743100

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2003

Design and synthesis of novel CCR3 antagonists.

As part of our investigation into the development of potent CCR3 antagonists, a series of piperidine analogues was designed and prepared. Exploration of the piperidine core examined both the basicity and the location of a nitrogen, as well as conformational variants. The bicyclo-piperidine 24c was found to be the most potent inhibitor of CCR3 with an IC(50) of 0.0082 microM in the binding assay and 0.0024 microM in the chemotaxis assay.

Drug Design↗

PubMed2003

Ultra high quality uHTS.

Explore the source record for details and available documents.

Drug Design↗

PubMed2003

Minding the Ps and Qs of genomewide analysis.

Explore the source record for details and available documents.

Drug Design↗