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PubMed · 12822726

Proliferative scarring.

Martin C Robson
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Abstract

Proliferative scarring in all organ systems is an enigma. Treatment has been difficult to impossible because the pathobiology of exuberant scarring and fibrosis was unclear. With the concept that proliferative scarring can be viewed on the healing trajectory and dissected into variations of the normal wound healing cellular processes mediated by soluble cytokine messengers, one can begin to understand how excessive scar formation occurs. Realizing that overexpression or dysregulated activity of the fibrogenic isoforms of TGF-beta and its attendant effect on apoptosis may be responsible for proliferative scarring opens the route to propose rational molecular manipulations that can be tested for the prevention or treatment of this enigmatic condition.

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CicatrixHumansPostoperative ComplicationsSurgical Procedures, OperativeWound HealingWounds, PenetratingJournal ArticleReview

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BibTeXRIS

Martin C Robson. 2003. Proliferative scarring.. https://doi.org/10.1016/s0039-6109(02)00197-4

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Minimal scars for scalp surgery.

BACKGROUND: As is well known, scars are the indelible ransom of any surgical procedure and the major obstacle confronting patients and surgeons from an aesthetic standpoint. Many patients opt against a surgical solution for this reason only or choose surgical techniques which are sometimes open to question, such as follicular unit extraction. OBJECTIVE: The objective was to change from narrow scars created at present to that of scars minimal to the naked eye, the subject of this article. METHODS: Following a clinical study of more than 100 cases, I present a new surgical technique enabling for the first time the creation of minimal scars to the naked eye. This technique is based on the role of the galea responsible for tension and secondary widening of scars in classical techniques and explains hypodermic incision to eliminate this wound tension, as well as the specific role of deepithelialization of the lower lip of the wound. RESULT: A minimal scar to the naked eye was obtained in most cases with this technique. CONCLUSION: Owing to this major improvement, I have switched from the conventional closure techniques to this new one.

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