Quantitative structure-activity relationships for predicting skin and eye irritation.

Grace Patlewicz; Rosemary Rodford; John D Walker

doi:10.1897/01-439

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Quantitative structure-activity relationships for predicting skin and eye irritation.

Grace Patlewicz·Rosemary Rodford·John D Walker

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Abstract

Recent quantitative structure-activity relationships (QSARs) for the prediction of skin and eye irritation were reviewed. The QSARs in these areas are hindered by the lack of quality in vivo data and by a lack of understanding of the mechanisms of action. Creation of appropriate data sets for experimentation would facilitate the development of robust QSARs for predicting skin and eye irritation.

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Animals Environmental Pollutants Eye Forecasting Humans Irritants Models, Animal Models, Theoretical Quantitative Structure-Activity Relationship Rabbits Reproducibility of Results Skin Tests Toxicity Tests Journal Article

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Grace Patlewicz, Rosemary Rodford, John D Walker. 2003. Quantitative structure-activity relationships for predicting skin and eye irritation.. https://doi.org/10.1897/01-439

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