PubMed · 12968424
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Maria Júlia Paes da Silva, Emiko Yoshikawa Egry. 2003. 2003: a new beginning..... https://doi.org/10.1590/s0080-62342003000100001
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Precision oncology relies on integrating tumour fraction, variant allele frequency, clonal haematopoiesis of indeterminate potential assessment, pathogenicity, and clinical context into next-generation sequencing interpretation, enabling biologically informed and clinically meaningful treatment decisions while reducing the risk of overinterpreting nontumour or nonactionable genomic alterations.