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Topical vitamin A acid in the treatment of acne vulgaris (a controlled multicenter trial).

M Gandola·G Argenziano·C Barba·R Bassi·M Binazzi·G Landi·L Levi·D Randazzo·F Serri·A P Villano
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Abstract

A controlled non-blind multicenter trial was conducted in 211 acne patients to test the activity of topical retinoic acid against sulfur-resorcinol--salicylic acid and placebo. Uniform evaluation criteria were used. After 8 weeks' treatment in comparable groups of patients, retinoic acid proved to be superior to the standard and to the placebo. The difference was statistically significant. Side effects were present in a number of patients treated with the active substances and with the placebo (mainly erythema), but rarely was the treatment discontinued.

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Acne VulgarisAdolescentAdultClinical Trials as TopicFemaleHumansMalePlacebosResorcinolsTretinoinVitamin AClinical TrialComparative StudyControlled Clinical TrialJournal Article

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M Gandola, G Argenziano, C Barba, R Bassi, M Binazzi, G Landi, L Levi, D Randazzo, F Serri, A P Villano. 1976-04-21. Topical vitamin A acid in the treatment of acne vulgaris (a controlled multicenter trial).. https://doi.org/10.1007/bf00558520

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