PubMed · 13253081
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D MARTIN. 1955. Museum techniques: fixation.. https://pubmed.ncbi.nlm.nih.gov/13253081/
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In 1997 agricultural workers, turned into looters, found an intact funerary site in the cloud forest in northeastern Peru. A prompt archaeological rescue project permitted the recovery of an important collection of mummies and artifacts that are providing important insights about the archaeology of the Chachapoya people that established in this area around 900 AD up to the Inca conquest of this territory around the year 1475. The mummies recovered showed evidence of cultural practices devised and used to assure the preservation of the human bodies. Such practices are also reported for among Chinchorro and Chiribaya mummies in the Andes. A cultural interpretation of these funerary activities is discussed connecting the practice of the cult to the ancestors to the access and management of resources and territory.
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Embalming is common, and it can create problems for the forensic scientist if a drug has been the cause death and this drug is also reactive toward the embalming fluid. Previous studies have focused on the tricyclic amines nortriptyline and desipramine. In the presence of formaldehyde, a typical component of embalming fluid, either of these two compounds can be rapidly converted to their methylated derivatives amitriptyline and imipramine, respectively. We have begun a larger project designed to determine the reactivity and reactions of a wide range of drugs with formaldehyde. We report here our results from fenfluramine, which, like the tricyclic amines, is reactive towards formaldehyde and is converted into its N-methyl derivative. The rate of conversion is dependent upon pH and formaldehyde concentration. Up to 100% conversion in 24 h was observed. In addition, we have also devised a simplified procedure for monitoring this process that may be useful for others working in this area. Finally, we note that the reactions of fenfluramine studied here and of amines in general with formaldehyde need to be considered when performing postmortem/postembalming forensic analysis.