PubMed · 13651540
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M J GARRETT. 1959. Haemangiosarcoma; a case report.. https://doi.org/10.1111/j.1365-2133.1959.tb13405.x
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Angiosarcoma is a rare, highly malignant tumor arising from endothelial cells of small blood vessels. They usually occur in the skin, deep soft tissues, breast and liver. Pleural angiosarcomas are extremely rare and are restricted to case reports in medical literature. It is very difficult to distinguish them from malignant mesotheliomas on clinical, radiological and even histopathological features. Immunohistochemistry is valuable in making the diagnosis, showing negative reactivity for mesothelial markers and positivity for vascular markers. Prognosis is generally dismal except in occasional cases where the disease is localized and amenable for surgical resection. We report a 55-year-old man who presented to us with chest pain, cough and hemoptysis and was diagnosed to have a pleural angiosarcoma.
Primary splenic angiosarcomas are rare neoplasms. They have aggressive behavior that frequently present with hematological abnormalities and metastatic disease. The diagnosis can only be made at surgery. Prognosis of this disease is poor. We present a rare case of primary splenic angiosarcoma with metastases in liver.