Separation processes in biotechnology. Aqueous two-phase separations.

P A Albertsson; G Johansson; F Tjerneld

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PubMed · 1366882

Separation processes in biotechnology. Aqueous two-phase separations.

P A Albertsson·G Johansson·F Tjerneld

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Abstract

Aqueous two-phase systems are useful for separation of a wide range of water-compatible substances (from peptides to cells). The selectivity of the separation normally increases with the size of the partitioned molecules or particles. The partition and separation capacity can be influenced in a number of ways, including electric charge, hydrophobicity, or specific ligand binding. Because of the simpleness in operation and high capacity, aqueous two-phase systems are well suited for large-scale purification of biomaterials such as enzymes and other specific proteins.

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Animals Biotechnology Cell Fractionation Proteins Solvents Journal Article Research Support, Non-U.S. Gov't Review

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P A Albertsson, G Johansson, F Tjerneld. 1990. Separation processes in biotechnology. Aqueous two-phase separations.. https://pubmed.ncbi.nlm.nih.gov/1366882/

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