Structural consequences of mutation.

C Eigenbrot; A A Kossiakoff

doi:10.1016/0958-1669(92)90160-k

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Structural consequences of mutation.

C Eigenbrot·A A Kossiakoff

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Abstract

The way a protein responds to mutation provides key insights into its architecture and energetics. Mutations are improving the understanding both of protein folding and stability, and of the adaptability of the hydrophobic core. The importance of intermolecular effects in crystal structures is being emphasized and new insights into the correspondence between crystal and solution structures are being developed.

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C Eigenbrot, A A Kossiakoff. 1992. Structural consequences of mutation.. https://doi.org/10.1016/0958-1669(92)90160-k

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