PubMed · 13882756
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H O CURTH. 1960. Malignant acanthosis nigricans.. https://pubmed.ncbi.nlm.nih.gov/13882756/
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Acanthosis nigricans in children is usually associated with obesity. Generalized acanthosis nigricans in childhood is rare. We report a 13-year-old boy with an 8-year history of generalized hyperpigmentation and velvety thickening of the skin. Despite an extensive physical and laboratory examination no evidence of underlying endocrinological or neoplastic disease was found.
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