PubMed Health⌕ Search

PubMed · 14185311

DIGITAL COMPUTERS IN THE BIOLOGICAL LABORATORY. COMPUTER PROCESSING OF DATA DURING EXPERIMENTS FACILITATES BIOLOGICAL RESEARCH.

Abstract

The use of digital techniques in the biological laboratory is relatively recent (22). At present, computer equipment is extremely expensive by contrast with conventional electronic equipment. However, the costs are decreasing, and these techniques are rapidly becoming more accessible as well as more powerful. Improvement in the fabrication, size, and compactness of solid-state devices promises rapid progress in computer technology of interest to the biologist. Through the use of integrated circuits it will be possible to make general-purpose computers no larger than a laboratory oscilloscope, as compared with the present desk-size console with auxiliary cabinets. Within a decade the speed of computation will increase by an order of magnitude, and the costs will decrease significantly. Moreover, it seems likely that the parts of a computer and the laboratory "interface" will become available as modular units. An experimenter will then be able to assemble the components necessary for a particular application and change them as required. At present, one has to modify commercial equipment for the nonstandard, biological uses. However, with modular building blocks of relatively small size and more reasonable cost the digital computer may become as familiar a laboratory tool tomorrow as the cathode-ray oscilloscope or the spectrophotometer is today.

Explore related subjects

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

R L SCHOENFELD, N MILKMAN. 1964-10-09. DIGITAL COMPUTERS IN THE BIOLOGICAL LABORATORY. COMPUTER PROCESSING OF DATA DURING EXPERIMENTS FACILITATES BIOLOGICAL RESEARCH.. https://doi.org/10.1126/science.146.3641.190

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

Lipid rafts: at a crossroad between cell biology and physics.

Membrane lateral heterogeneity is accepted as a requirement for the function of biological membranes and the notion of lipid rafts gives specificity to this broad concept. However, the lipid raft field is now at a technical impasse because the physical tools to study biological membranes as a liquid that is ordered in space and time are still being developed. This has lead to a disconnection between the concept of lipid rafts as derived from biochemical and biophysical assays and their existence in the cell. Here, we compare the concept of lipid rafts as it has emerged from the study of synthetic membranes with the reality of lateral heterogeneity in biological membranes. Further application of existing tools and the development of new tools are needed to understand the dynamic heterogeneity of biological membranes.

Biology↗