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Fluorescent 2-pyrimidinone nucleoside in parallel-stranded DNA.

D N Kaluzhny·S N Mikhailov·E V Efimtseva·O F Borisova·V L Florentiev·A K Shchyolkina·T M Jovin
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Abstract

Stretches of parallel-stranded (ps) double-helical DNA can arise within antiparallel-stranded (aps) Watson-Crick DNA in looped structures or in the presence of sequence mismatches. Here we studied an effect of a pyrimidinone-G (PG) base pair on the stability and conformation of the ps DNA to explore whether P is useful as a structural probe.

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Base Pair MismatchBase PairingBase SequenceDNADeoxyribonucleosidesFluorescent DyesNucleic Acid ConformationNucleic Acid DenaturationOligodeoxyribonucleotidesPyrimidinonesThermodynamicsJournal ArticleResearch Support, Non-U.S. Gov't

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D N Kaluzhny, S N Mikhailov, E V Efimtseva, O F Borisova, V L Florentiev, A K Shchyolkina, T M Jovin. Fluorescent 2-pyrimidinone nucleoside in parallel-stranded DNA.. https://doi.org/10.1081/ncn-120023020

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