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MoMLV reverse transcriptase regulates its own expression.

Christina Bradley·Robert Craigie
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Abstract

A precise ratio of Gag:Gag-Pol expression is required for assembly of infectious retroviral virions. In this issue of Cell, Orlova et al. show that MoMLV reverse transcriptase binds the translation release factor eRF1, and that this interaction promotes translation readthrough to make Gag-Pol.

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AnimalsFusion Proteins, gag-polMiceMoloney murine leukemia virusPeptide Termination FactorsProtein BindingProtein BiosynthesisRNA-Directed DNA PolymeraseSubstrate SpecificityVirionVirus ReplicationCommentJournal Article

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Christina Bradley, Robert Craigie. 2003-10-31. MoMLV reverse transcriptase regulates its own expression.. https://doi.org/10.1016/s0092-8674(03)00850-x

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