Acetan:glucomannan interactions--a molecular modeling study.

Rengaswami Chandrasekaran; Srinivas Janaswamy; Victor J Morris

doi:10.1016/j.carres.2003.08.018

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Acetan:glucomannan interactions--a molecular modeling study.

Rengaswami Chandrasekaran·Srinivas Janaswamy·Victor J Morris

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Abstract

X-ray fiber diffraction patterns from deacylated acetan and glucomannan (konjac mannan) blends are diagnostic of good orientation and modest polycrystallinity. The meridional reflection on the sixth layer line suggests that the binary complex is a 6-fold helix of pitch 55.4 A. A molecular modeling study incorporating this information reveals that a double helix in which one strand is acetan and the other glucomannan is stereochemically feasible. While the backbone and side groups are sufficiently flexible to allow the chains to associate with the same or opposite polarity, the parallel model is superior in terms of unit cell packing. The results are compatible with the observed synergy; namely the weak gelation behavior of the complex. The molecular model can be generalized for the binary system when acetan is replaced by xanthan or glucomannan by galactomannan.

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Acetylation Algorithms Binding Sites Carbohydrate Conformation Computer Simulation Glucans Hydrogen Bonding Least-Squares Analysis Mannans Models, Molecular Molecular Structure Polysaccharides, Bacterial X-Ray Diffraction Journal Article Research Support, Non-U.S. Gov't

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Rengaswami Chandrasekaran, Srinivas Janaswamy, Victor J Morris. 2003-11-21. Acetan:glucomannan interactions--a molecular modeling study.. https://doi.org/10.1016/j.carres.2003.08.018

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