[Effect of himantane on the rat embryo development].

A D Durnev; N M Smol'nikova; E P Nemova; E A Val'dman; N I Avdiunina; B M Piatin; S B Seredenin

PubMed · 14743708

[Effect of himantane on the rat embryo development].

A D Durnev·N M Smol'nikova·E P Nemova·E A Val'dman·N I Avdiunina·B M Piatin·S B Seredenin

Abstract

Himantane introduced via a gastric tube to pregnant rats in a dose of 10, 30, 50, and 100 mg/kg produced a dose-dependent embryotoxic and teratogenic action. An analysis of the experimental results and published data suggests that the embryotoxicity of himantane can be related to its general toxic action upon the organism of pregnant female rats.

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Abnormalities, Drug-Induced Adamantane Animals Antiparkinson Agents Embryonic and Fetal Development Female Lethal Dose 50 Pregnancy Pregnancy Complications Rats English Abstract Journal Article

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A D Durnev, N M Smol'nikova, E P Nemova, E A Val'dman, N I Avdiunina, B M Piatin, S B Seredenin. [Effect of himantane on the rat embryo development].. https://pubmed.ncbi.nlm.nih.gov/14743708/

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