PubMed · 14851298
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F BORDET. 1951-06-28. [Tonsillitis and sulfamides].. https://pubmed.ncbi.nlm.nih.gov/14851298/
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[reaction: see text] An efficient intermolecular 1,3-dipolar cycloaddition of a variety of nitrones to pentafluorophenyl (PFP) vinylsulfonate is described. The transformation produces stable "reversed" cycloadducts of unprecedented stereo- and regioselectivity. Subsequent amine displacement of the PFP moiety furnished functionalized sulfonamide products in good yields.
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