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PubMed · 14980197

Coordinating synaptic growth without being a nervous wreck.

Catherine A Collins·Aaron DiAntonio
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Abstract

The function and regulation of actin-cytoskeletal dynamics during synaptic growth is poorly understood. In this issue of Neuron, Coyle et al. report the identification of nervous wreck (nwk), a synapse-specific adaptor molecule in Drosophila that regulates synaptic growth and morphology via Wasp, a well-characterized mediator of actin dynamics.

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ActinsAnimalsCell DifferentiationCytoskeletonDrosophila ProteinsMicrofilament ProteinsNerve Tissue ProteinsNervous SystemNeuromuscular JunctionWiskott-Aldrich Syndrome ProteinCommentNews

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Catherine A Collins, Aaron DiAntonio. 2004-02-19. Coordinating synaptic growth without being a nervous wreck.. https://doi.org/10.1016/s0896-6273(04)00078-9

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