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PubMed · 15070060

Thyroid function and pregnancy status in broodmares.

Travis B Meredith·Ina Dobrinski
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Abstract

OBJECTIVE: To determine whether thyroid function was associated with pregnancy status in broodmares. DESIGN: Prospective study. ANIMALS: 79 Thoroughbred and Standardbred broodmares between 2 and 22 years old. PROCEDURE: Serum triiodothyronine (T3) concentration was measured before and 2 hours after i.v. administration of thyrotropin releasing hormone (TRH), and serum thyroxine (T4) concentration was measured before and 4 hours after TRH administration. Pregnancy status was monitored by means of transrectal ultrasonography beginning 16 days after ovulation. RESULTS: Baseline T3 and T4 concentrations varied widely. In all mares, serumT3 concentration increased in response to TRH administration. Serum T4 concentration increased in response toTRH administration in all but 2 mares. Pregnancy rate was 76%. Baseline and stimulated serum T3 and T4 concentrations were not significantly different between mares that became pregnant and those that did not. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that decreased thyroid function is uncommon in mares and poor thyroid function is not a common cause of infertility. Thus, the practice of indiscriminately treating broodmares with thyroid hormone to enhance fertility appears questionable at this time.

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AnimalsFemaleHorsesOvulationPregnancyPregnancy RatePregnancy, AnimalProspective StudiesThyroid GlandThyrotropin-Releasing HormoneThyroxineTriiodothyronineJournal ArticleResearch Support, Non-U.S. Gov't

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Travis B Meredith, Ina Dobrinski. 2004-03-15. Thyroid function and pregnancy status in broodmares.. https://doi.org/10.2460/javma.2004.224.892

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