PubMed · 15123274
What makes epothilones stick?
Abstract
The potent epothilone tubulin polymerization promoters have been studied extensively by synthetic and SAR approaches. The paper by Buey et al. (, this issue of Chemistry & Biology) adds a new depth of mechanistic understanding by a careful analysis of the tubulin polymerization mechanism of the epothilones.
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David G I Kingston. 2004. What makes epothilones stick?. https://doi.org/10.1016/j.chembiol.2004.02.009
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