Resetting the clock: Dexras1 defines a path.

Russell N Van Gelder

doi:10.1016/j.neuron.2004.08.029

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Resetting the clock: Dexras1 defines a path.

Russell N Van Gelder

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Abstract

The signaling pathways by which light and activity shift the circadian clock are not well understood. In this issue of Neuron, Cheng et al. analyze mice lacking Dexras1 (a Ras family GTPase protein) and demonstrate an important role for G(i/o) signaling mediating both photic and nonphotic phase shifts of the circadian clock.

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Animals Biological Clocks Circadian Rhythm GTP-Binding Protein alpha Subunits, Gi-Go GTP-Binding Proteins Glutamic Acid Humans Mice Receptors, N-Methyl-D-Aspartate Retinal Ganglion Cells Signal Transduction ras Proteins Comment Journal Article Review

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Russell N Van Gelder. 2004-09-02. Resetting the clock: Dexras1 defines a path.. https://doi.org/10.1016/j.neuron.2004.08.029

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