PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 1537273

Remembrance: NIH scientists develop specific assays for human chorionic gonadotropin.

G D Hodgen
View original source ↗Export metadata ↓

Abstract

The source did not provide an abstract. Follow the original record for more information.

Explore related subjects

Chorionic GonadotropinEndocrinologyHistory, 20th CenturyHumansNational Institutes of Health (U.S.)United StatesHistorical ArticleJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

G D Hodgen. 1992. Remembrance: NIH scientists develop specific assays for human chorionic gonadotropin.. https://doi.org/10.1210/endo.130.3.1537273

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1992

Elevated second trimester maternal serum beta-HCG concentrations and subsequent adverse pregnancy outcome.

Previous studies have found an association between elevated second trimester maternal serum alpha-fetoprotein (MS-AFP), in the absence of fetal anomalies, and adverse pregnancy outcome. We studied the association between elevated second trimester maternal serum beta-HCG, now also routinely measured by prenatal screening programs, and adverse pregnancy outcome by reviewing retrospectively the pregnancy outcomes among women with markedly elevated midtrimester beta-HCG in our prenatal screening program. Seven (0.23%) of 3,000 consecutively screened women had a serum beta-HCG above 5 MOM. Four (57%) of these 7 women had an adverse pregnancy outcome including severe preeclampsia (n = 2), abruptio placentae (n = 1), or preterm labor (n = 1). A concurrently elevated MS-AFP was found in only one of these 4 patients. Elevated mid-trimester maternal serum beta-HCG may be an independent risk factor for subsequent adverse pregnancy outcomes.

Chorionic Gonadotropin↗